Clspn

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August undefined, 2024

http://magcst.com/gn/?cLspN/ WebClaspin is a protein that in humans is encoded by the CLSPN gene. Function. Xenopus claspin is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in the presence of DNA templates in Xenopus egg extracts. The human gene appears to be the homolog Xenopus claspin and its function has not been ...

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WebUSP7 was originally identified as a protein associated with the ICP0 protein of herpes simplex virus ( HSV ), hence the name Herpesvirus Associated USP (HAUSP). ICP0 is an E3-ubiquitin ligase that is involved in ubiquitination and subsequent degradation of itself and certain cellular proteins. USP7 has been shown to regulate the auto ... WebNov 27, 2024 · CLSPN claspin Gene ID: 63967, updated on 27-Nov-2024 Gene type: protein coding. See all available tests in GTR for this gene; Go to complete Gene record … spotify users over the years

A nine-gene signature as prognostic biomarker in gastric

WebCLSPN c.2028+16G>A was significantly associated with familial breast cancer, with a higher frequency of the G allele among familial breast cancer cases when compared to controls. Statistically significant differences were found when comparing c.2028+16G>A allelic frequencies between controls and the glioma group (p < 0.05).The data revealed an … WebMar 21, 2024 · CLSPN (Claspin) is a Protein Coding gene. Diseases associated with CLSPN include Ataxia-Telangiectasia and Seckel Syndrome . Among its related pathways are Homology Directed Repair … WebThere are 129 common target genes involved in 3 pathways and 28 functional annotations. Finally, nine key target genes of GC (BRCA1, RAD51, KIF11, ERCC6L, BRIP1, TIMELESS, CDC25A, CLSPN and NCAPG2) were identified, and a prognostic model was successfully constructed with a good predictive ability. spotify vermin \u0026 the beachrat

Clspn

WebCLSPN. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. Amygdala Basal ganglia Thalamus Midbrain Pons Medulla oblongata Hippocampal formation Spinal cord White matter Cerebral cortex Cerebellum Choroid plexus Hypothalamus Retina Thyroid gland Parathyroid gland Adrenal gland Pituitary gland … WebCancers 2024, 12, 2396 3 of 25 Table 1. Claspin gene (CLSPN) variants detected in breast cancer and glioma patients. Variant Rs Number Gene Location aa Change fBC sBC Glioma Controls c.-68C>T ...

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WebSep 1, 2024 · CLSPN is a checkpoint with an important role in cell cycle progression. The regulatory role of CLSPN in malignant tumours has recently attracted extensive attention …

WebRequired for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures … WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CLSPN.

WebJan 8, 2024 · CLSPN is a potential biomarker associated with poor prognosis in low-grade gliomas based on a multi-database analysis. Overexpression of claspin promotes … WebFeb 15, 2024 · Background:Claspin (CLSPN) expression is acknowledged as a poor clinical prognostic factor in various tumors.However, the clinical characteristics and biological functions of CLSPN in prostate cancer (PCa) are still to be clarified. The aim of our study was to evaluate the association of CLSPN expression during PCa progression and its …

WebDescription: Homo sapiens claspin (CLSPN), transcript variant 1, mRNA. (from RefSeq NM_022111) RefSeq Summary (NM_022111): The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient …

WebThe Clarkson College LPN to BSN program is designed for the LPN nurse who is interested in earning a Bachelor’s degree and obtaining the position of a registered … shenandoah river land for saleWebDec 1, 2024 · 2 years. Online + Campus. A public institution, Seward County Community College helps learners prepare for the workforce through associate and certificate programs in nursing. Although the … shenandoah river levels lurayWebCLSPN was correlated with shorter biochemical recurrence (BCR)-free survival and overall survival. After we knocked-out CLSPN in DU145 and LNCaP cells, the in vitro phenotypic results showed that the ability of the knockouts to proliferate, migrate, and invade was attenuated; but that apoptosis was promoted. spotify uverworldWebApr 11, 2024 · CLSPN is a cell cycle checkpoint adaptor protein that plays an important role in DNA replication . Kobayashi et al. [ 49 ] proposed that CLSPN may be a key regulatory factor in the progression of GC and demonstrated that its expression level was related to the prognosis through immunohistochemical analysis. spotify uwp appWebCLSPN. A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed. On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l ... spotify velvet willowWebPrEST Antigen CLSPN [Catalog No.: ATL-APrEST90640] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT … spotify version as of 2023WebSep 6, 2016 · A composite score derived from the four genes that showed expression changes in the direction consistent with that expected on the basis of preclinical data (specifically, CCNE2, CLSPN, and MCM10 as downregulated set and HIST1H2BD as upregulated gene) showed a consistent trend indicating target engagement at all … spotify us office