WebCyclophosphamide is approved to be used alone or with other drugs to treat: Acute … Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and … See more Cyclophosphamide is used to treat cancers and autoimmune diseases. It is used to quickly control the disease. Due to its toxicity, it is replaced as soon as possible by less toxic drugs. Regular and frequent laboratory … See more Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening circumstances in the mother. Additional relative contraindications to the use of … See more Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) in the liver to active metabolites. The main active metabolite is 4-hydroxycyclophosphamide, which exists in See more As reported by O. M. Colvin in his study of the development of cyclophosphamide and its clinical applications, Phosphoramide … See more Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting, bone marrow suppression, stomach ache, hemorrhagic cystitis, diarrhea, … See more The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH. Phosphoramide … See more The abbreviation CP is common, although abbreviating drug names is not best practice in medicine. See more

Axi-cel Retreatment in Relapsed/Refractory LBCL

WebThe anticancer drug cyclophosphamide induces granulosa cell apoptosis and is detoxified by glutathione (GSH) conjugation. We previously showed that both cyclophosphamide treatment and GSH depletion induced granulosa cell apoptosis in rats, but the role of GSH in apoptosis in human ovarian cells has … WebCyclophosphamide is also called anhydrous cyclophosphamide, ciclofosfamide, ciclofosfamida, cyclophosphamid, cyclophosphamidum, cytophosphane, and ledoxina. It has the chemical formula of C7H15Cl2N2O2P. Cyclophosphamide is a medicine that is available in the tablet and injection forms. It has low solubility in water, sparingly solubility … braintree florida

Cyclophosphamide Oral: Uses, Side Effects, Interactions ... - WebMD

WebApr 5, 2024 · Drug: axi-cel. Axicabtagene ciloleucel (Axi-cel) is an autologous anti-CD-19 chimeric antigen receptor (CAR) T-cell therapy approved by FDA in 2024 for the treatment of patients with relapsed/refractory large B-cell lymphoma (R/R LBCL). Now, it is the standard treatment for these patients recommended by NCCN and other guidelines. WebIn the US, Cyclophosphamide (cyclophosphamide systemic) is a member of the drug … WebThe meaning of CYCLOPHOSPHAMIDE is an immunosuppressive and antineoplastic … braintree flower shop