Folh1是什么
WebDetected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in … The three domains of the extracellular portion of GCPII—the protease, apical and C-terminal domains—collaborate in substrate recognition. The protease domain is a central seven-stranded mixed β-sheet. The β-sheet is flanked by 10 α-helices. The apical domain is located between the first and the second strands of the central β-sheet of the protease domain. The C-terminal domain is an Up-Down-Up-Down four-helix bundle. The apical, protease and C-terminal domains creat…
Folh1是什么
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WebThe gene view histogram is a graphical view of mutations across FOLH1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Web1 day ago · 【共同社4月13日电】在全球大受欢迎的日本作家村上春树（74岁）的小说新作《城市及其不确定的墙》13日发售。这是继《刺杀骑士团长》（全2册）之后时隔约6年 …
WebSDS-PAGE View Larger. 2 μg/lane of Recombinant Cynomolgus Monkey PSMA/FOLH1/NAALADase I His-tag (Catalog # 10437-ZN) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing a band at ~100 kDa under reducing conditions. Reconstitution Calculator. WebFOLH1 INFORMATION. Proteini. Full gene name according to HGNC. Folate hydrolase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. FOLH1 (FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
WebJan 2, 2024 · Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role of PSMA has not been explored, and its role in prostate cancer remained elusive. Filling this gap, we demonstrate that in ... WebJan 18, 2024 · 2.1. FOLH1 mRNA and PSMA Protein Levels in the PCa Cell Lines LAPC4, LNCaP, C4-2 and PC3. To analyze the influence of increased and decreased AR activity on FOLH1 expression, the AR-positive castration sensitive cell lines LAPC4, LNCaP, and the castration-resistant LNCaP sub-cell line C4-2 was used [].In addition, the AR negative …
WebHuman Prostate Specific Membrane Antigen (PSMA), also known as folate hydrolase I (FOLH1), is a 750-amino acid type II membrane glycoprotein, which is primarily expressed in normal human prostate epithelium and is upregulated in prostate cancer, including metastatic disease. We have cloned and sequenced the mouse homolog of PSMA, …
WebRecombinant Human PSMA/FOLH1/NAALADase1 (rhPSMA) (Catalog # 4234-ZN) Dilute rhPSMA to 0.4 µg/mL in Assay Buffer. Dilute Substrate to 40 µM with Assay Buffer. … glitched happy faceWeb谷氨酸能神经元是中枢神经系统内最为重要的兴奋性神经元。. 当神经元中谷氨酸被囊泡谷氨酸转运体 (vesicular glutamate transporters,VGLUTs)转运进入突触囊泡 (synaptic … glitched heartWebDec 8, 2024 · 此外,psma的官方基因名为叶酸水解酶1(folh1),反映其在叶酸摄取中的主要作用。细胞内叶酸浓度被认为是一把双刃剑,低水平与染色体损伤易感性增加有关,而高水平则 … body visualizer sizing demoglitched helloWebFOLH1 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, FOLH1 Genome Browser, FOLH1 References FOLH1 - Explore an overview of FOLH1, with a … glitched homemade wings ajWebFeb 20, 2002 · In stably transfected LNCaP cells, the FOLH1 promoter/leader region produced a 21% downregulation in response to androgens, while addition of the enhancer resulted in a 45% downregulation. These results demonstrate significant upregulation of transcription by the PSMA promoter/enhancer, with specificity for the LNCaP prostate … body vitality complex 50+WebFOLH1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … glitched holiday sweater