P-hydroxyphenylacetate
WebAug 19, 2003 · p-Hydroxyphenylacetate (HPA) hydroxylase (HPAH) was purified from Acinetobacter baumannii and shown to be a two-protein component enzyme. The small component (C 1) is the reductase enzyme with a subunit molecular mass of 32 kDa.C 1 alone catalyses HPA-stimulated NADH oxidation without hydroxylation of HPA. C 1 is a … Web4-Hydroxyphenylacetate decarboxylase (4Hpad) is an Fe/S cluster containing glycyl radical enzyme (GRE), which catalyses the last step of tyrosine fermentation in clostridia, generating the bacteriostatic p-cresol. The respective activating enzyme (4Hpad-AE) displays two cysteine-rich motifs in addition to the classical S-adenosylmethionine (SAM ...
P-hydroxyphenylacetate
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WebA novel glycyl radical enzyme catalysing the formation of p-cresol Eur. J. Biochem. 268 1363-1372 2001 Clostridioides difficile ... Zauner, S.; Andrei-Selmer, L.C.; Selmer, T. Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase. A small subunit, HpdC, is essential for catalytic activity Eur. J. Biochem. 271 ... Webp-Hydroxyphenylacetate-3-hydroxylase, an inducible enzyme isolated from the soil bacterium Pseudomonas putida, catalyzes the conversion of p-hydroxyphenylacetate to 3,4-dihydroxyphenylacetate. The enzyme requires two protein components: a flavoprotein and a colorless protein referred to as the coupling protein. The flavoprotein alone in the …
Web4-Hydroxyphenylacetate decarboxylase (HPAD) is a new member of GRE family [64]. This enzyme catalyzes a Kolbe-type decarboxylation [65] by using a protein-based glycyl/thiyl … WebJun 23, 2006 · p -Hydroxyphenylacetate hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of p -hydroxyphenylacetate (HPA) to form 3,4-dihydroxyphenylacetate (DHPA). The enzyme system is composed of two proteins: an FMN reductase (C) and an oxygenase that uses FMNH – (C ).
Webp-Hydroxyphenylacetate-3-hydroxylase, an inducible enzyme isolated from the soil bacterium Pseudomonas putida, catalyzes the conversion of p-hydroxyphenylacetate to … Web효소에서는 3-히드록시페닐아세테이트 6-히드록실라아제(EC 1.14.13.63)가 화학반응을 촉진하는 효소다.. 3-hydroxyphenylacetate + NAD(P)H + H + 2 + O 2,5-dihydhydroxyphenylacetate + NAD(P)+ + HO 2. 이 효소의 5가지 기판은 3-히드록시페닐아세테이트, NADH, NADPH, H +, O인데 2 반해 4가지 제품은 2,5 …
Webp-Hydroxyphenylacetate decarboxylase from Clostridium difficile catalyses the decarboxylation of p-hydroxyphenylacetate to yield the cytotoxic compound p-cresol. The …
WebI'm currently involved in research involving an enzymatic cascade reaction to transform pesticides, herbicides, and phenolic compounds into high-value-added chemicals like firefly luciferin and its analogs. At the School of Biomolecular Science and Engineering (BSE), Vidyasirimedhi Institute of Science and Technology (VISTEC), Thailand, I am also … florian hubnerWebFeb 19, 2024 · p-Hydroxyphenylacetate is a tyrosine metabolic product of certain Clostridia bacteria. Elevated levels are associated with Clostridia overgrowth, small intestinal bowel … greatsword expertise new worldgreatsword fantasy artWeb4-Hydroxyphenylacetic acid is obtained by reducing 4-hydroxymandelic acid with elemental phosphorus and iodine. [3] Uses [ edit] In industry, 4-hydroxyphenylacetic acid is an … florian hudry cycling projectWebOct 5, 2024 · Aldolases catalyze the reversible reactions of aldol condensation and cleavage and have strong potential for the synthesis of chiral compounds, widely used in pharmaceuticals. Here, we investigated a new Class II metal aldolase from the p -hydroxyphenylacetate degradation pathway in Acinetobacter baumannii, 4-hydroxy … florian howetWebApr 15, 2024 · p-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii catalyzes the hydroxylation of p-hydroxyphenylacetate (HPA) to yield 3,4-dihydroxyphenylacetate (DHPA). In this study, we investigated whether variants of the oxygenase component (C 2) could catalyze hydroxylation of 4-hydroxyphenylethylamines … greatsword farmerWebp-hydroxyphenylacetate: ( hī-droks'ē-fen'il-as'ĕ-tāt ), A minor side product of l -tyrosine degradation that is elevated in the urine in cases of neonatal tyrosinemia and in type II tyrosinemia. florian hubel dws